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1.
Impact of chemical structure on the in vitro hydrolysis of fatty esters of 2-ethylhexanoic acid or 2-ethylhexanol and extrapolation to the in vivo situation.
Regul Toxicol Pharmacol
; 137: 105315, 2023 Jan.
Article
in English
| MEDLINE | ID: mdl-36494001
2.
Effect of chain length and branching on the in vitro metabolism of a series of parabens in human liver S9, human skin S9, and human plasma.
Regul Toxicol Pharmacol
; 122: 104918, 2021 Jun.
Article
in English
| MEDLINE | ID: mdl-33741472
3.
Extrapolation of systemic bioavailability assessing skin absorption and epidermal and hepatic metabolism of aromatic amine hair dyes in vitro.
Toxicol Appl Pharmacol
; 287(2): 139-148, 2015 Sep 01.
Article
in English
| MEDLINE | ID: mdl-26028483
4.
Structure-activity relationship read-across and transcriptomics for branched carboxylic acids.
Toxicol Sci
; 191(2): 343-356, 2023 02 17.
Article
in English
| MEDLINE | ID: mdl-36583546
5.
Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids.
Toxicol In Vitro
; 69: 104990, 2020 Dec.
Article
in English
| MEDLINE | ID: mdl-32882340
6.
Intrinsic relative potency of a series of pyrrolizidine alkaloids characterized by rate and extent of metabolism.
Food Chem Toxicol
; 131: 110523, 2019 Sep.
Article
in English
| MEDLINE | ID: mdl-31129256
7.
Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach.
J Med Chem
; 49(15): 4745-61, 2006 Jul 27.
Article
in English
| MEDLINE | ID: mdl-16854081
8.
Suitability of the in vitro Caco-2 assay to predict the oral absorption of aromatic amine hair dyes.
Toxicol In Vitro
; 32: 1-7, 2016 Apr.
Article
in English
| MEDLINE | ID: mdl-26578466
9.
Corrigendum to partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids.
Toxicol In Vitro
; 71: 105050, 2021 Mar.
Article
in English
| MEDLINE | ID: mdl-33223358
10.
Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.
J Med Chem
; 51(19): 6055-66, 2008 Oct 09.
Article
in English
| MEDLINE | ID: mdl-18771254
11.
Novel pyrazolopiperazinone- and pyrrolopiperazinone-based MCH-R1 antagonists.
Bioorg Med Chem Lett
; 17(3): 657-61, 2007 Feb 01.
Article
in English
| MEDLINE | ID: mdl-17174091
12.
The efficacy and cardiac evaluation of aminomethyl tetrahydronaphthalene ketopiperazines: a novel class of potent MCH-R1 antagonists.
Bioorg Med Chem
; 15(5): 2092-105, 2007 Mar 01.
Article
in English
| MEDLINE | ID: mdl-17236777
13.
Aminomethyl tetrahydronaphthalene ketopiperazine MCH-R1 antagonists--Increasing selectivity over hERG.
Bioorg Med Chem Lett
; 17(3): 819-22, 2007 Feb 01.
Article
in English
| MEDLINE | ID: mdl-17107796
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